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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5549c708bdee67dee99f09ab260b0a44703a46163424ad1f2a5a49795ff30e6b' 
  AND token = '4KZaj1VZLSuvT6a8I55FBNRqOTC6XFLNgEAgmy5hdfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}