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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3c15ae3de91e7df00d7ded4484f34f3bc6edcce328c769647dfd682e876b3e' 
  AND token = 'bY1M3k2Ys1LCVfq4V44Rk5NlSo99oMU1SelD05Oz8cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}