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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed57a503aca606b71a1d06a5b5b53e9192dfd5d9d1981f065e5404be9d4fe16' 
  AND token = 'Cw49R7FkKkxWd+Lnput5V+cpJT7WBo/cUtkbghKpO7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}