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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c269106fd71afd650a01fee43fc9653f81cb71a3b9e3e98c3cc0d0132bd3d57' 
  AND token = 'GbD5M3T2/2HE7eIwql966n0vgVGvUOksuqLqLUahNug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}