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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c15637850b89fb0c43b97966125367534dd12a80c2a9bb02f7ce27571f9542' 
  AND token = 'tsFMT+1vcaCUdFnPeq4odY0v123xuAf5asF3ZJSNZu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}