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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f8d209b50af3cf7831384db5fff509c93b52f7644adbc9f765c05c1101a8c7' 
  AND token = 'F9SfRwdTy/5QcZI3KRezTvrEMT7fDE9tSXIYDe/qRZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}