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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46864cd9043fbf48a9e81f6610a4a54c1a1b1be78670edfc1af1312339e9db37' 
  AND token = '9B8epsitjjQx1N3bdB4cHCGRiVlo13FSkZUaReA7uKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}