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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745b4af80d1795974d2372a397aa8f03a2eb7be6492c9b9f06f9fad98d9ee8f0' 
  AND token = 'McPyEymPuYa5yRReL0HeM88ZibZM3wP3alv9FxxRkGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}