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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720f82e0035400f6635b2dca5b0fcbc29418742a34ab84f422f2a2adce56c3cb' 
  AND token = 'gB2EoKlSH7WIG5+W5I/dpXk04EuL7dAhEbBuIkLUysI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}