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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccc9bb3dccc396827cecd8e2aa9da8829e60f7b99c4bf6f803dcc33fee455220' 
  AND token = '8YWHJgpma23PhgCHTzwJPxR5LiQfSG+eQn47/L30u2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}