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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e9e366306a4e91bb4c3a57c9259c8d65f0d497a3cefbd813d5e1d2dada5ef8' 
  AND token = 'JzygdKq69LsOBTEPrhO+NOFsgfVEykI/fYCfSuRioac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}