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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b36446a301d26ac7f7e855c6949ff14fa8e82048211191ad57dbfc3133b71f4' 
  AND token = 'lwNl91s1xc9bMhYevT7UkkrXaL57veORvTXx1IxXS0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}