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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d151018f327d15f6b247c8a04f30eeca66b53d0692b842cdb0169ad520ed9bd' 
  AND token = '0Qp1OBe3MVbnkfGoupOjUXdMi8HEF+O8sp/35ZwAvjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}