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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d4731c9f404edc7f608c32372eaf6fb0b5dbf104bc9bd5b5a7e22f3ebb7ff7' 
  AND token = 'GusC3y4KI/XIc707ZQ33tcAzJawehQ+OQX/ClKrPh4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}