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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb29899ba75e357fff90c000683a9c8c20fdcf5c325600b3957dec9dd359547' 
  AND token = 'e1Le4kZMClaL++kn3MycS8Q7J03+PUPl7hyyGGYCk4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}