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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28c0df9a0618273748f333977dbcae1011bc674926bcad11763fcd4f0eb0d41' 
  AND token = 'eyHtzA8tasACKU/fUUM88Jq49Lm5CARMLuHFiOf4nmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}