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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be95f4e3e3d06861a21dc9b2f5401defe07caf1b97738f16a23d4451d589aca' 
  AND token = 'yrDI+W8QjeiBLvLKF75TYQVvBbicNu9rx4WbPGeRgLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}