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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afea3590511d68303a047794c236be51289b01097170b159724e6210219b7f97' 
  AND token = 'PoB5mONz3wzMxw4eSmhsQzUSRLXCu9xoUs4S5+4bqDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}