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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8444edcca4e45f9418daa3f1b4587a66261fbc9239f6c30f53cb328ac0edfdfd' 
  AND token = 'aRB6rIDS6Hm4tsPqbOfZYjGD2Lwg27DtWaEBU40arrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}