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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a2f60628623d1d6e528cffce46183e5b24866dbef643b6b1ce9a32d669b5e50' 
  AND token = 'cFVdyfT23fTAki3WuytI9fS2d1+yvAklLkC6ZdlvvWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}