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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f87072e3dd5ebe3b3e1eba64e658b75a407433c23d6c0d246014d8b61f4d3032' 
  AND token = '+MpUoUOq+cQj3zF61ixaxdaKy6vDb5nOSIuvdUXGHOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}