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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0819015b0cdf5363e9db2d7b55597948d85b4b3da6c65006232d30099c2a505a' 
  AND token = 'aMlySkd8Xi9ZLmYQuRn+qhpvPFS1G5on15+O7PlVTK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}