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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b42b87739797a1532e36fe4b4fadcb8a076aac9d1570e18594099c23c1f670' 
  AND token = '5hw70RKPhfKgo284BvMKmKD2r2WHhcNCTC9AMexnCoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}