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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301e540a65df6d31ae28817131da1c9ae4bba0927b00ce23d04c1682cc2e08f8' 
  AND token = 'mstSGao3XzVS+AmSJ+b6ecW8oObP/ZLuJL2ZfE5jRi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}