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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d0c989b1c0a481eca3fe87b78816b7925524b1dbc3612b6a64039f94761242' 
  AND token = 'B2simLjp+7oHY5jTd35NyalEuTmppfz/sFk5b8QP/E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}