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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ea64bcca434b52a26ac2c10f6334dac1a6843cc02a949067003b8c9dd1d8fc' 
  AND token = '2i11isbbbC8jSjkDYmBmvH0hhsWj2ydPe2HDm6TGJtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}