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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb6e1be88f77d72827bdb053b5b79ad75c3aaef2caab4b7cbb994c734b48b42' 
  AND token = '8IxoDEVHe5Om7jTUt5UVaQFjQkutXIn+UBD0SfbHJYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}