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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e8ca7c986f7fe543082b38e382db322f2abf28b8144f07d88d08c2dd2c21fa' 
  AND token = 'QOBSz8oOQl28OH+k9wkhlmCymD1efd+tyvddz7K/QkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}