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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df52acd160bb05aa23143e638a73b5a1f65c02250b4ca326320ab61c165b3ff' 
  AND token = 'VfGKXh8HVs/iojUwsXCQp9tk69q4oidNMYzjWtuklY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}