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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80aaec154eb0585b4031953050e07818796c99d4ff683bb8b39d45ed672458f' 
  AND token = '78ytLyui/T+2bt27VYc0xhK6EA4kjACttd9ODu5RHLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}