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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004ae83d6a8fd925dbf4340f97b0b47258ffbd63f49ce6c373c424a556ba0b72' 
  AND token = 'LI76lWvQLgkLB4bZXYEwzDvsZBg8Lv8fqefcod9nGQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}