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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f65c375d295348cb506fa5c328eb965eb97690b18e154b35fefbc213fa63e3' 
  AND token = 'A27Cn9jJpYKx9ApULrKypk3L6Z2N2K/tGdPWXJxjDLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}