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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be8e1ba187be3ea30b2cacce9db1418476b2edbfb0710ae2768b2e029c6f792' 
  AND token = 'iG4e5LNbm3Y6CexSd5M/HmZyiL/dGnO/25Py/5yoILg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}