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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '117226fbbe1511c591a2b4cfbe89591b40806309f15f00a35315722a941992b2' 
  AND token = 'XRs8Nr/3SxiYPPcIVcU0jC/6pnviaXwOXfcMe7aDwTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}