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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd41576dc3c09c72e38f6fc2d4a7d950f92c9182d62048d198e9d28a456304c' 
  AND token = 'Ds+7hr5fbtG7gJR+ij3pRREjEG8aBnh2EgD4Hf1dHl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}