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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d3e5bbb8f24ede028ef5ce59cbad171b6184f74b12a6dcf18bba0af485fb0c' 
  AND token = 'GYhgXI7bXAOyaqYMgzyEoJ9WkAHHypU0wtJQ54FWBxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}