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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '391acf6e0c20bc6bdb472a8a350072d1f2cd250e0ec9ed435fe41119f26f243c' 
  AND token = 'eXrY7NX71KCPMKwvNU+JI4elFf1/839ksA5WHsS/2Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}