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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a195238bf156b376b46ad2115b6009ea24d941c110324a2e62a1543e07998e' 
  AND token = 'm6BNl2/Z2SPZ3lYaWUCOi0dZynKr+OnNHLPCOAuYKE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}