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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '873962da0f7eb553d10a70e4a0d1c947c6aa9cb749344af4bd414230edb0d9a7' 
  AND token = 'f3WqKEk2R7Am1IRPdx8HJ986VX6hyZ+W7Hj32FV5KeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}