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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a9983eeec17e1a5edf0c630332607f4accdc9c921a2be6d81f46ff2a1ab1a0' 
  AND token = 'zb5BSBQwD/kg0MaKuLBSh5DPRJdVVk81xzpCQPGdj1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}