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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9eb213b3fdc2a939094cf9afb272bb5f86df624575a92309f73f04b08d9170' 
  AND token = 'p/1g6GH14TJICz9oZEAagIEGh3bkkbZAej4QmjsUzsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}