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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1a718decab064a6e3087ad8bdd8e251c2d6c4b3e384b4be63a4bb4949dd231' 
  AND token = '8DY+KSWLR0C47W0JF6i9WREquHfCe/OzpVEwrUb1BS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}