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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c85e44b5a63966df2fb2a8a21c2e8e6ec233b8080a67862b53b20157b3986f7' 
  AND token = 'uLJvqOpfI8xnbWene7odUWSlAox1taYi3XhN0OisoBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}