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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0252ad05bd5ee80f8cb8b5b6c9a7845cdb20d1260c213ac7e5093aee87845954' 
  AND token = 'X7gCs4UZNhwL72fjZvZk0JeY8Fz1rTTQbXD4jTTXfbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}