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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b0822af27a062d8747029784b0821f4e6afa0e8db2d08e1e5a4394cd0e10da' 
  AND token = 'rO1MzUTYGB6TXxWHuGkAsZXlbbgsgPoRhiMW2bfxdCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}