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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6f9de92a97f4f2907258cd056b45d4b72f0456ed04f63f70c4492845e43703' 
  AND token = 'slOW/LzQu8v+FG+/AGw1MMvF54J0clKsZ4lrtp2fDG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}