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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a183c92ef474090404a040171c6c3d80e59051588813d930c244e07badf966c4' 
  AND token = 'vn8cwXlVjEKwxS9RBW/o7BZcrYrSFaXEDHOvl2I4RvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}