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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5368b0c49e5eaa0014f9905041bcdcf238f3a7122f648d351fab5b60c784fb' 
  AND token = 'LZw0PGi674b5+1mALcYYWENfi2VEeZC7EicUVbpVjjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}