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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4d9690735d15e1a419eed394742b6ea3d51b21a4c5dd5eee18c9cd8a2d3f353' 
  AND token = '2qQrMgir7I+ziHvRWdNBjEThuKCwPt21UMYPvVzjebg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}