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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a22cc37dc7148b25b902da4593a8aeff5f5ecda4932971bf182f024e449d0fd' 
  AND token = 'sJs1AqZwhjrHoaQpsuJC4wveo1T3Nj/7qBUM+LHmNeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}